Aids Incidence Explain Why Aids Patients Have Higher Incidence Of Cancers?
Explain why aids patients have higher incidence of cancers? - aids incidence
Since imunocompromised Sothey that are sensitive.
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immune compromised
Everyone has cancer cells in our body is destroyed in our genes, but our immune system. If the immune system is weak, the result is cancer.
less immune system. A healthy immune system can help to fight cancer, but with AIDS, the immune system is so low is that much easier and faster spread of cancer ... So generally people are dying with AIDS, of something else, such as cancer or pneumonia. Not in the real diesas themselves.
First, these patients have a low immunity to cancer.2nd sensitive to all is a theory that the same virus cancer, such as pear can cause Kaposi.
Ok,
Cancers occur after an increase of germline mutations of cancer cells, the arguments ii'll well epithlial cells. If this increase in the epithelial cells the ability to grow independently and followed without cell-cell interactions by a process of apoptosis (programmed cell death) is a rule. Apoptosis (in this case) occurs when that binds to receptors on T cells on the surface of epithelial cells and resolved (if desired) that is dangerous.
Now, there are currently two theories in immunology is the self / non-event itself, the other is the least used, but valid only as a threat scenarios. Well, the self / non-self is that his theory to achieve the cancer, and you say ... But even cancer antigens. Enter the risk hypothesis explains that the body does not recongise me and me, but dangerous and not dangerous. However, if a single cancer cell is to bind to T cells and apoptosis are detected. AIDS (Acquired Immune itself deficiancy) is characterized by the absence of CD4 + T-cells characterized that are capable of other cells, apoptosis ASWELl, B cells and induce plasma cells and begin secreting antibodies. As it is, among AIDS patients, these cells are present or present but in small quantity possibilities relatvily apoptosis of epithelial cells is much smaller than a healthy person. Therefore, the cell is allowed to divide and share. As you will, the cells do not need a connection with the unit cells can also break the primary tumor and grow to form a secondary tumor.
There's also something about the CD25 + T cells, their frequency in cancer cells, these cells may contribute to the growth of tumor cells and often in patients with AIDS as CD25 + T cells were not aware the ability to auto-immune diseases Assistance (entirley what but they are) I would on a side note, add, because in fact, still considered, but an interesting topic
Hope this helps
Try reading some newspapers online publishing PubMed or Janeway C. Immunobiology 6
Because they no immune system to fight, as opposed to healthy people
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